The rapid growth of artificial intelligence has accelerated data generation,which increasingly exposes the limitations faced by traditional computational architectures,particularly in terms of energy consumption and d...The rapid growth of artificial intelligence has accelerated data generation,which increasingly exposes the limitations faced by traditional computational architectures,particularly in terms of energy consumption and data latency.In contrast,data-centric computing that integrates processing and storage has the potential of reducing latency and energy usage.Organic optoelectronic synaptic transistors have emerged as one type of promising devices to implement the data-centric com-puting paradigm owing to their superiority of flexibility,low cost,and large-area fabrication.However,sophisticated functions including vector-matrix multiplication that a single device can achieve are limited.Thus,the fabrication and utilization of organic optoelectronic synaptic transistor arrays(OOSTAs)are imperative.Here,we summarize the recent advances in OOSTAs.Various strategies for manufacturing OOSTAs are introduced,including coating and casting,physical vapor deposition,printing,and photolithography.Furthermore,innovative applications of the OOSTA system integration are discussed,including neuromor-phic visual systems and neuromorphic computing systems.At last,challenges and future perspectives of utilizing OOSTAs in real-world applications are discussed.展开更多
This study employs the comprehensive index method and the coefficient of variation method to explore the integration mechanism of regional culture and tourism.It measures the integration development degree of cultu-re...This study employs the comprehensive index method and the coefficient of variation method to explore the integration mechanism of regional culture and tourism.It measures the integration development degree of cultu-re and tourism subsystems in 16 prefecture-level cities in Anhui Province.Additionally,the decision-making trial and evaluation laboratory(DEMATEL)method is used to investigate the integration mechanism.The results indicate the following:From 2012 to 2021,the comprehensive index,integration degree,and integration development degree of cultural subsystems in the 16 prefecture-level cities in Anhui Province exhibited noticeable periodic changes.Bet-ween 2015 and 2019,the growth rate in eastern prefecture-level cities was significantly faster than that in central and western cities.In 2019,all regions—eastern,central,and western—experienced a downward trend,and the spatial difference in recovery growth in 2020 was minimal.Within the cultural and tourism integration system,the industry foundation and activity scale of the cultural subsystem are interdependent,while the industry foundation of the tourism subsystem results from the market scale.The central factors are primarily focused on the industr-ial base and the activity or market scale of the criterion layer of both subsystems.Conversely,the economic con-tribution of the criterion layer of the two subsystems has a minimal impact on centrality.展开更多
This study examines the “V + Dào” construction as a state change event through the lens of the Event Integration Hypothesis. It focuses on how these constructions represent state changes, exploring distinctions...This study examines the “V + Dào” construction as a state change event through the lens of the Event Integration Hypothesis. It focuses on how these constructions represent state changes, exploring distinctions between “change” and “stasis”. Using a corpus-based approach, the analysis covers the semantic and syntactic features of “V + Dào” constructions and their event integration patterns. The findings highlight the distribution of agency, animacy, and support relations in state change events, emphasizing the complex interaction of internal and external event integrations and their correlation with the conceptual primitives of change and transition. This study offers insights into the lexicalization and grammaticalization processes of the “V + Dào” construction, and potentially the broader verb-complement constructions in Mandarin.展开更多
Objective:To explore the effect of medical and nursing integration mode on the nursing care of patients with inguinal hernia treated by tension-free repair.Methods:A total of 76 cases of inguinal hernia patients admit...Objective:To explore the effect of medical and nursing integration mode on the nursing care of patients with inguinal hernia treated by tension-free repair.Methods:A total of 76 cases of inguinal hernia patients admitted to the hospital from September 2023 to August 2024 were selected as study subjects.They were divided into 38 cases each in the control group and the observation group by using the random number table method.The patients in the control group were cared for by the traditional postoperative care mode and the patients in the observation group were given additional medical and nursing care based on the control group,and were observed and analyzed for pain relief,infection,hospital stay,and hospital costs.Results:The VAS score of patients in the observation group was(7.91±2.21)at 1d postoperation and(11.04±3.24)at 1d postoperation in the control group,which was significantly lower than that of the control group,with a statistically significant difference(P<0.05),and the VAS score of the patients at 6 months postoperation was(4.82±1.81),which was not statistically significant when compared with that of the control patients(4.79±1.45),which was not statistically different from those of the control group(P>0.05);3 cases of infection occurred in the at 3d,accounting for the total number of observation group postoperative patients(7.89%),and compared with control group with postoperative 5 cases of infection occurred in the 3 days,accounting for of the total number of patients(13.16%),the postoperative infection rate of the patients in the observation group was significantly reduced,and the difference was statistically significant(P<0.05).The number of hospitalization days as well as the hospitalization costs of the observation group were significantly lower than those of the control group,and the difference was statistically significant(P<0.05).Conclusion:The integrated model of medical care has significant advantages in the care of patients with inguinal hernia treated with tension-free repair,which can effectively alleviate early postoperative pain,reduce the rate of infection,shorten the length of hospital stay,and reduce the cost of hospitalization.展开更多
With the rapid development of China’s economy,the demand for high-end talents in the field of engineering technology is becoming increasingly prominent.Engineering doctors,as an important force in this field,have a d...With the rapid development of China’s economy,the demand for high-end talents in the field of engineering technology is becoming increasingly prominent.Engineering doctors,as an important force in this field,have a direct impact on the progress of national technological innovation and the upgrading of industrial structure.Currently,there are still some issues in the university-enterprise collaboration for engineering doctor training in China,such as unclear cooperation mechanisms and responsibility divisions,insufficient corporate participation and enthusiasm,and imperfect evaluation and feedback mechanisms.This paper aims to explore the university-enterprise collaborative training path of engineering doctors from the perspective of deep integration,analyzing multiple dimensions including training objectives,curriculum design,practical sessions,mentor teams,and evaluation systems,in order to provide reference for the reform and practice of engineering doctor training in China.展开更多
With the advent of the information age,people’s production and life are more closely connected with the Internet.Internet technology not only improves the production efficiency,but also provides great convenience for...With the advent of the information age,people’s production and life are more closely connected with the Internet.Internet technology not only improves the production efficiency,but also provides great convenience for people’s life.At present,people’s requirements for computer information technology are gradually increasing.When we look directly at the information transmission and storage capacity,computer information technology cannot meet the market demand.Due to rapid development,the integration of artificial intelligence(AI)can enable the development of computer information technology.In this paper,computer information technology and artificial intelligence integration act as a starting point,and the integration of the development of the two is analyzed for reference.展开更多
This paper presents a case study of the collaborative integration between the School of Information and Software Engineering at the University of Electronic Science and Technology of China(UESTC)and SI-TECH,highlighti...This paper presents a case study of the collaborative integration between the School of Information and Software Engineering at the University of Electronic Science and Technology of China(UESTC)and SI-TECH,highlighting the complementary advantages of both the University and the enterprise.By jointly establishing research institutes and engaging in diversified collaborative initiatives,the University and the enterprise have embarked on a pathway of School-enterprise Integration.Through a virtuous cycle of cooperation and continuous advancement,they have explored a comprehensive talent cultivation model in“5G”software engineering innovation practices based on this integration.Furthermore,this endeavor aims to facilitate the transformation of technological achievements and provides valuable insights for fostering innovative talents in the field of electronic information through enhanced integration between the University and the enterprise.展开更多
With the rapid development of medical and nursing combinations,the application of humanistic care in medical and nursing combination institutions is getting more attention.Elderly institutions are the main carrier of ...With the rapid development of medical and nursing combinations,the application of humanistic care in medical and nursing combination institutions is getting more attention.Elderly institutions are the main carrier of elderly services in China,and the demand for humanistic care among the elderly in elderly institutions is also getting higher and higher,but at present,the humanistic care ability of the nursing staff in China's medical and nursing combined institutions is low.In recent years,the state vigorously promoted the development of traditional Chinese medicine,traditional Chinese medicine nursing contains a wealth of humanistic ideas,which can provide another solution for the lack of humanistic care in healthcare institutions.This paper discusses the ideological value,practical value and talent cultivation value of TCM humanistic nursing in medical care combination,aiming to provide a reference basis for improving the quality of humanistic nursing in medical care combination organizations.展开更多
In response to the problem of improving practical abilities of students in the process of cultivating innovative talents in the field of financial technology in the specialized software college,this paper analyzes the...In response to the problem of improving practical abilities of students in the process of cultivating innovative talents in the field of financial technology in the specialized software college,this paper analyzes the characteristics and applicability of problem-based learning(PBL)method,proposes a PBL course integration design scheme for the integration of business and technology in the field of financial technology,and provides corresponding course cases.The plan described in this article has been jointly demonstrated by experts from schools and enterprises and has received good feedback.展开更多
In recent years,managing rural living environments has become a vital component of the rural revitalization strategy.Jiangsu Province,rich in economic and cultural resources,has accumulated valuable experience in expl...In recent years,managing rural living environments has become a vital component of the rural revitalization strategy.Jiangsu Province,rich in economic and cultural resources,has accumulated valuable experience in exploring rural environmental governance by integrating culture and tourism.This research analyzes the practical logic of rural environmental governance in Jiangsu from both theoretical and practical perspectives.It emphasizes the importance of integrating culture and tourism to enhance environmental governance while addressing the associated challenges.The results show that the integration of culture and tourism not only enhances rural ecological environments and living facilities but also boosts regional economic development and the preservation of cultural resources.Nevertheless,there are still challenges in aspects such as the collaboration of stakeholders,the establishment of long-term mechanisms,and the application of digital technologies.Based on real cases in Jiangsu,this study suggests optimization strategies and policy recommendations to improve rural environmental governance within the framework of cultural and tourism integration.展开更多
The advancement of Internet of Things(IoT)technology is driving industries toward intelligent digital transformation,highlighting the crucial role of software engineering.Despite this,the integration of software engin...The advancement of Internet of Things(IoT)technology is driving industries toward intelligent digital transformation,highlighting the crucial role of software engineering.Despite this,the integration of software engineering into IoT engineering education remains underexplored.To address this gap,the School of Software at North University of China,in collaboration with QST Innovation Technology Group Co.,Ltd.(QST),has developed an innovative educational mechanism.This initiative focuses on the software engineering IoT track and optimizes the teaching process through the outcome-based education(OBE)concept.It incorporates military-industrial characteristics,introduces advanced information and technology curricula,and enhances laboratory infrastructure.The goal is to cultivate innovative talents with unique capabilities,thereby fostering the comprehensive development and application of IoT technology.展开更多
This study explores the integration path of ideological and political education in the course Design Thinking and Expression of environmental art design,aiming to enhance students’innovative thinking,social responsib...This study explores the integration path of ideological and political education in the course Design Thinking and Expression of environmental art design,aiming to enhance students’innovative thinking,social responsibility,and awareness of sustainable development.Based on the core philosophy of design thinking(people-oriented,problem-solving,and interdisciplinary collaboration)and the elements of ideological and political education in courses(moral education,cultural confidence,sustainable development,and social equity),the study proposes implementation paths for optimizing course objectives,adjusting course content,innovating teaching methods,and optimizing the evaluation system.Through project-based learning,situational teaching,and interdisciplinary collaboration,combined with practical cases such as historical district renewal,environmental design for rural revitalization,and green commercial space design,it has been verified that the effective integration of ideological and political elements in courses can enhance students’cultural identity,sense of social responsibility,and design innovation ability.This study provides theoretical support and practical demonstration for the ideological and political reform of environmental art design courses.In the future,interdisciplinary collaboration can be further deepened,social practice applications can be expanded,the evaluation system can be improved,and the systematic development of ideological and political courses can be promoted.展开更多
The performance of optical interconnection has improved dramatically in recent years.Silicon-based optoelectronic heterogeneous integration is the key enabler to achieve high performance optical interconnection,which ...The performance of optical interconnection has improved dramatically in recent years.Silicon-based optoelectronic heterogeneous integration is the key enabler to achieve high performance optical interconnection,which not only provides the optical gain which is absent from native Si substrates and enables complete photonic functionalities on chip,but also improves the system performance through advanced heterogeneous integrated packaging.This paper reviews recent progress of silicon-based optoelectronic heterogeneous integration in high performance optical interconnection.The research status,development trend and application of ultra-low loss optical waveguides,high-speed detectors,high-speed modulators,lasers and 2D,2.5D,3D and monolithic integration are focused on.展开更多
As the manufacturing process of silicon-based integrated circuits(ICs)approaches its physical limit,the quantum effect of silicon-based field-effect transistors(FETs)has become increasingly evident.And the burgeoning ...As the manufacturing process of silicon-based integrated circuits(ICs)approaches its physical limit,the quantum effect of silicon-based field-effect transistors(FETs)has become increasingly evident.And the burgeoning carbon-based semiconductor technology has become one of the most disruptive technologies in the post-Moore era.As one-dimensional nanomaterials,carbon nanotubes(CNTs)are far superior to silicon at the same technology nodes of FETs because of their excellent electrical transport and scaling properties,rendering them the most competitive material in the next-generation ICs technology.However,certain challenges impede the industrialization of CNTs,particularly in terms of material preparation,which significantly hinders the development of CNT-based ICs.Focusing on CNT-based ICs technology,this review summarizes its main technical status,development trends,existing challenges,and future development directions.展开更多
The Chinese express delivery industry processes nearly 110 billion items in 2022,averaging an annual growth rate of 200%.Among the various types of sorting systems used for handling express items,cross-belt sorting sy...The Chinese express delivery industry processes nearly 110 billion items in 2022,averaging an annual growth rate of 200%.Among the various types of sorting systems used for handling express items,cross-belt sorting systems stand out as the most crucial.However,despite their high degree of automation,the workload for operators has intensified owing to the surging volume of express items.In the era of Industry 5.0,it is imperative to adopt new technologies that not only enhance worker welfare but also improve the efficiency of cross-belt systems.Striking a balance between efficiency in handling express items and operator well-being is challenging.Digital twin technology offers a promising solution in this respect.A realization method of a human-machine integrated digital twin is proposed in this study,enabling the interaction of biological human bodies,virtual human bodies,virtual equipment,and logistics equipment in a closed loop,thus setting an operating framework.Key technologies in the proposed framework include a collection of heterogeneous data from multiple sources,construction of the relationship between operator fatigue and operation efficiency based on physiological measurements,virtual model construction,and an online optimization module based on real-time simulation.The feasibility of the proposed method was verified in an express distribution center.展开更多
Critical care medicine focuses on understanding the pathophysiological mechanisms and treatment approaches for life-threatening conditions,including sepsis,severe trauma/burns,hemorrhagic shock,heatstroke,and acute pa...Critical care medicine focuses on understanding the pathophysiological mechanisms and treatment approaches for life-threatening conditions,including sepsis,severe trauma/burns,hemorrhagic shock,heatstroke,and acute pancreatitis,all of which have high incidence rates.These conditions are primarily characterized by acute multi-organ dysfunction,with sudden onset,severe illness,and high mortality rates.Additionally,critical care treatment demands substantial medical resources,imposing significant economic burdens on patients’families and society.In recent years,critical care medicine has achieved notable progress,especially in multidisciplinary integration with immunology-based fields.Collaboration across disciplines has not only accelerated advancements in critical care but also propelled the rapid development of modern immunology.This paper provides an overview and assessment of the cross-disciplinary fusion between critical care medicine and immunology,exploring how these fields related extensions mutually enhance each other.It further analyzes China’s potential to become a global leader in this area within the next 5 to 10 years.展开更多
El Niño-Southern Oscillation(ENSO)is the strongest interannual climate mode influencing the coupled ocean-atmosphere system in the tropical Pacific,and numerous dynamical and statistical models have been develope...El Niño-Southern Oscillation(ENSO)is the strongest interannual climate mode influencing the coupled ocean-atmosphere system in the tropical Pacific,and numerous dynamical and statistical models have been developed to simulate and predict it.In some simplified coupled ocean-atmosphere models,the relationship between sea surface temperature(SST)anomalies and wind stress(τ)anomalies can be constructed by statistical methods,such as singular value decomposition(SVD).In recent years,the applications of artificial intelligence(AI)to climate modeling have shown promising prospects,and the integrations of AI-based models with dynamical models are active areas of research.This study constructs U-Net models for representing the relationship between SSTAs andτanomalies in the tropical Pacific;the UNet-derivedτmodel,denoted asτUNet,is then used to replace the original SVD-basedτmodel of an intermediate coupled model(ICM),forming a newly AI-integrated ICM,referred to as ICM-UNet.The simulation results obtained from ICM-UNet demonstrate their ability to represent the spatiotemporal variability of oceanic and atmospheric anomaly fields in the equatorial Pacific.In the ocean-only case study,theτUNet-derived wind stress anomaly fields are used to force the ocean component of the ICM,the results of which also indicate reasonable simulations of typical ENSO events.These results demonstrate the feasibility of integrating an AI-derived model with a physics-based dynamical model for ENSO modeling studies.Furthermore,the successful integration of the dynamical ocean models with the AI-based atmospheric wind model provides a novel approach to ocean-atmosphere interaction modeling studies.展开更多
In this study,we present a novel nodal integration-based particle finite element method(N-PFEM)designed for the dynamic analysis of saturated soils.Our approach incorporates the nodal integration technique into a gene...In this study,we present a novel nodal integration-based particle finite element method(N-PFEM)designed for the dynamic analysis of saturated soils.Our approach incorporates the nodal integration technique into a generalised Hellinger-Reissner(HR)variational principle,creating an implicit PFEM formulation.To mitigate the volumetric locking issue in low-order elements,we employ a node-based strain smoothing technique.By discretising field variables at the centre of smoothing cells,we achieve nodal integration over cells,eliminating the need for sophisticated mapping operations after re-meshing in the PFEM.We express the discretised governing equations as a min-max optimisation problem,which is further reformulated as a standard second-order cone programming(SOCP)problem.Stresses,pore water pressure,and displacements are simultaneously determined using the advanced primal-dual interior point method.Consequently,our numerical model offers improved accuracy for stresses and pore water pressure compared to the displacement-based PFEM formulation.Numerical experiments demonstrate that the N-PFEM efficiently captures both transient and long-term hydro-mechanical behaviour of saturated soils with high accuracy,obviating the need for stabilisation or regularisation techniques commonly employed in other nodal integration-based PFEM approaches.This work holds significant implications for the development of robust and accurate numerical tools for studying saturated soil dynamics.展开更多
Background Mastitis caused by multiple factors remains one of the most common and costly disease of the dairy industry.Multi-omics approaches enable the comprehensive investigation of the complex interactions between ...Background Mastitis caused by multiple factors remains one of the most common and costly disease of the dairy industry.Multi-omics approaches enable the comprehensive investigation of the complex interactions between mul-tiple layers of information to provide a more holistic view of disease pathogenesis.Therefore,this study investigated the genomic and epigenomic signatures and the possible regulatory mechanisms underlying subclinical mastitis by integrating RNA sequencing data(mRNA and lncRNA),small RNA sequencing data(miRNA)and DNA methylation sequencing data of milk somatic cells from 10 healthy cows and 20 cows with naturally occurring subclinical mastitis caused by Staphylococcus aureus or Staphylococcus chromogenes.Results Functional investigation of the data sets through gene set analysis uncovered 3458 biological process GO terms and 170 KEGG pathways with altered activities during subclinical mastitis,provided further insights into subclin-ical mastitis and revealed the involvement of multi-omics signatures in the altered immune responses and impaired mammary gland productivity during subclinical mastitis.The abundant genomic and epigenomic signatures with sig-nificant alterations related to subclinical mastitis were observed,including 30,846,2552,1276 and 57 differential methylation haplotype blocks(dMHBs),differentially expressed genes(DEGs),lncRNAs(DELs)and miRNAs(DEMs),respectively.Next,5 factors presenting the principal variation of differential multi-omics signatures were identified.The important roles of Factor 1(DEG,DEM and DEL)and Factor 2(dMHB and DEM),in the regulation of immune defense and impaired mammary gland functions during subclinical mastitis were revealed.Each of the omics within Factors 1 and 2 explained about 20%of the source of variation in subclinical mastitis.Also,networks of impor-tant functional gene sets with the involvement of multi-omics signatures were demonstrated,which contributed to a comprehensive view of the possible regulatory mechanisms underlying subclinical mastitis.Furthermore,multi-omics integration enabled the association of the epigenomic regulatory factors(dMHBs,DELs and DEMs)of altered genes in important pathways,such as‘Staphylococcus aureus infection pathway’and‘natural killer cell mediated cyto-toxicity pathway’,etc.,which provides further insights into mastitis regulatory mechanisms.Moreover,few multi-omics signatures(14 dMHBs,25 DEGs,18 DELs and 5 DEMs)were identified as candidate discriminant signatures with capac-ity of distinguishing subclinical mastitis cows from healthy cows.Conclusion The integration of genomic and epigenomic data by multi-omics approaches in this study provided a better understanding of the molecular mechanisms underlying subclinical mastitis and identified multi-omics candidate discriminant signatures for subclinical mastitis,which may ultimately lead to the development of more effective mastitis control and management strategies.展开更多
Objective:We investigated the relation between man papillomavirus(HPV)integration status and the immediate risk of cervical intraepithelial neoplasia(CIN),as well as the triage strategy based on HPV integration test.M...Objective:We investigated the relation between man papillomavirus(HPV)integration status and the immediate risk of cervical intraepithelial neoplasia(CIN),as well as the triage strategy based on HPV integration test.Methods:4086 women aged 20 to 65 years in China were enrolled in 2015 for a prospective,population-based,clinical observational study to evaluate the triage performance of HPV integration.Cervical exfoliated cells were collected for HPV testing and cytologic test.If high-risk HPV was positive,HPV integration test was performed at baseline,2-year and 5-year follow-up.Results:At baseline,HPV integration was positively correlated with the severity of cervical pathology,ranging from 5.0%(15/301)in normal diagnosis,6.9%(4/58)in CIN1,31.0%(9/29)in CIN2,70%(14/20)in CIN3,and 100%(2/2)in cervical cancer(P<0.001).Compared with cytology,HPV integration exhibits comparable sensitivity and negative predictive value for the diagnosis of CIN3+,higher specificity(92.8%[90.2%-95.4%]vs.75.5%[71.2%-79.8%],P<0.001)and higher positive predictive value(36.4%[22.1%-50.6%]vs.15.2%[8.5%-21.8%],P<0.001).HPV integration testing strategy yielded a significantly lower colposcopy referral rate than cytology strategy(10.7%[44/410]vs.27.3%[112/410],P<0.001).The HPV integration-negative group exhibited the lowest immediate risk for CIN3+(1.6%)and accounted for the largest proportion of the total population(89.3%),when compared with the normal cytology group(risk,1.7%;proportion,72.7%).Conclusion:As a key molecular basis for the development of cervical cancer,HPV integration might be a promising triage strategy for HPV-positive patients.展开更多
基金supported by the National Key Research and Development Program of China(2021YFA1101303)the National Natural Science Foundation of China(62374115)the Innovation Program of Shanghai Municipal Education Commission(2021-01-07-00-07-E00096).
文摘The rapid growth of artificial intelligence has accelerated data generation,which increasingly exposes the limitations faced by traditional computational architectures,particularly in terms of energy consumption and data latency.In contrast,data-centric computing that integrates processing and storage has the potential of reducing latency and energy usage.Organic optoelectronic synaptic transistors have emerged as one type of promising devices to implement the data-centric com-puting paradigm owing to their superiority of flexibility,low cost,and large-area fabrication.However,sophisticated functions including vector-matrix multiplication that a single device can achieve are limited.Thus,the fabrication and utilization of organic optoelectronic synaptic transistor arrays(OOSTAs)are imperative.Here,we summarize the recent advances in OOSTAs.Various strategies for manufacturing OOSTAs are introduced,including coating and casting,physical vapor deposition,printing,and photolithography.Furthermore,innovative applications of the OOSTA system integration are discussed,including neuromor-phic visual systems and neuromorphic computing systems.At last,challenges and future perspectives of utilizing OOSTAs in real-world applications are discussed.
基金The Anhui Province Philosophy Social Science Planning General Project(AHSKY2022D135)The Anhui University Discipline(Professional)Top Talents Academic Funding Project(gxbj ZD2021015)。
文摘This study employs the comprehensive index method and the coefficient of variation method to explore the integration mechanism of regional culture and tourism.It measures the integration development degree of cultu-re and tourism subsystems in 16 prefecture-level cities in Anhui Province.Additionally,the decision-making trial and evaluation laboratory(DEMATEL)method is used to investigate the integration mechanism.The results indicate the following:From 2012 to 2021,the comprehensive index,integration degree,and integration development degree of cultural subsystems in the 16 prefecture-level cities in Anhui Province exhibited noticeable periodic changes.Bet-ween 2015 and 2019,the growth rate in eastern prefecture-level cities was significantly faster than that in central and western cities.In 2019,all regions—eastern,central,and western—experienced a downward trend,and the spatial difference in recovery growth in 2020 was minimal.Within the cultural and tourism integration system,the industry foundation and activity scale of the cultural subsystem are interdependent,while the industry foundation of the tourism subsystem results from the market scale.The central factors are primarily focused on the industr-ial base and the activity or market scale of the criterion layer of both subsystems.Conversely,the economic con-tribution of the criterion layer of the two subsystems has a minimal impact on centrality.
文摘This study examines the “V + Dào” construction as a state change event through the lens of the Event Integration Hypothesis. It focuses on how these constructions represent state changes, exploring distinctions between “change” and “stasis”. Using a corpus-based approach, the analysis covers the semantic and syntactic features of “V + Dào” constructions and their event integration patterns. The findings highlight the distribution of agency, animacy, and support relations in state change events, emphasizing the complex interaction of internal and external event integrations and their correlation with the conceptual primitives of change and transition. This study offers insights into the lexicalization and grammaticalization processes of the “V + Dào” construction, and potentially the broader verb-complement constructions in Mandarin.
文摘Objective:To explore the effect of medical and nursing integration mode on the nursing care of patients with inguinal hernia treated by tension-free repair.Methods:A total of 76 cases of inguinal hernia patients admitted to the hospital from September 2023 to August 2024 were selected as study subjects.They were divided into 38 cases each in the control group and the observation group by using the random number table method.The patients in the control group were cared for by the traditional postoperative care mode and the patients in the observation group were given additional medical and nursing care based on the control group,and were observed and analyzed for pain relief,infection,hospital stay,and hospital costs.Results:The VAS score of patients in the observation group was(7.91±2.21)at 1d postoperation and(11.04±3.24)at 1d postoperation in the control group,which was significantly lower than that of the control group,with a statistically significant difference(P<0.05),and the VAS score of the patients at 6 months postoperation was(4.82±1.81),which was not statistically significant when compared with that of the control patients(4.79±1.45),which was not statistically different from those of the control group(P>0.05);3 cases of infection occurred in the at 3d,accounting for the total number of observation group postoperative patients(7.89%),and compared with control group with postoperative 5 cases of infection occurred in the 3 days,accounting for of the total number of patients(13.16%),the postoperative infection rate of the patients in the observation group was significantly reduced,and the difference was statistically significant(P<0.05).The number of hospitalization days as well as the hospitalization costs of the observation group were significantly lower than those of the control group,and the difference was statistically significant(P<0.05).Conclusion:The integrated model of medical care has significant advantages in the care of patients with inguinal hernia treated with tension-free repair,which can effectively alleviate early postoperative pain,reduce the rate of infection,shorten the length of hospital stay,and reduce the cost of hospitalization.
基金supported in part by the 2023 College Student Innovation and Entrepreneurship Training 430 Program Project of China(Grant No.202310699159)2024 Graduate Education Comprehensive Reform,Development and Innovation Project of Northwestern Polytechnical University(Grant No.KCJG202432)2023 Northwestern Polytechnical University Degree and Postgraduate Education Research Funding(Grant No.2023YMs014)。
文摘With the rapid development of China’s economy,the demand for high-end talents in the field of engineering technology is becoming increasingly prominent.Engineering doctors,as an important force in this field,have a direct impact on the progress of national technological innovation and the upgrading of industrial structure.Currently,there are still some issues in the university-enterprise collaboration for engineering doctor training in China,such as unclear cooperation mechanisms and responsibility divisions,insufficient corporate participation and enthusiasm,and imperfect evaluation and feedback mechanisms.This paper aims to explore the university-enterprise collaborative training path of engineering doctors from the perspective of deep integration,analyzing multiple dimensions including training objectives,curriculum design,practical sessions,mentor teams,and evaluation systems,in order to provide reference for the reform and practice of engineering doctor training in China.
文摘With the advent of the information age,people’s production and life are more closely connected with the Internet.Internet technology not only improves the production efficiency,but also provides great convenience for people’s life.At present,people’s requirements for computer information technology are gradually increasing.When we look directly at the information transmission and storage capacity,computer information technology cannot meet the market demand.Due to rapid development,the integration of artificial intelligence(AI)can enable the development of computer information technology.In this paper,computer information technology and artificial intelligence integration act as a starting point,and the integration of the development of the two is analyzed for reference.
文摘This paper presents a case study of the collaborative integration between the School of Information and Software Engineering at the University of Electronic Science and Technology of China(UESTC)and SI-TECH,highlighting the complementary advantages of both the University and the enterprise.By jointly establishing research institutes and engaging in diversified collaborative initiatives,the University and the enterprise have embarked on a pathway of School-enterprise Integration.Through a virtuous cycle of cooperation and continuous advancement,they have explored a comprehensive talent cultivation model in“5G”software engineering innovation practices based on this integration.Furthermore,this endeavor aims to facilitate the transformation of technological achievements and provides valuable insights for fostering innovative talents in the field of electronic information through enhanced integration between the University and the enterprise.
文摘With the rapid development of medical and nursing combinations,the application of humanistic care in medical and nursing combination institutions is getting more attention.Elderly institutions are the main carrier of elderly services in China,and the demand for humanistic care among the elderly in elderly institutions is also getting higher and higher,but at present,the humanistic care ability of the nursing staff in China's medical and nursing combined institutions is low.In recent years,the state vigorously promoted the development of traditional Chinese medicine,traditional Chinese medicine nursing contains a wealth of humanistic ideas,which can provide another solution for the lack of humanistic care in healthcare institutions.This paper discusses the ideological value,practical value and talent cultivation value of TCM humanistic nursing in medical care combination,aiming to provide a reference basis for improving the quality of humanistic nursing in medical care combination organizations.
文摘In response to the problem of improving practical abilities of students in the process of cultivating innovative talents in the field of financial technology in the specialized software college,this paper analyzes the characteristics and applicability of problem-based learning(PBL)method,proposes a PBL course integration design scheme for the integration of business and technology in the field of financial technology,and provides corresponding course cases.The plan described in this article has been jointly demonstrated by experts from schools and enterprises and has received good feedback.
基金2022 Key Research Project of Philosophy and Social Sciences at Nanjing Tech University Pujiang Institute,“The Subject-Object Relationship and Its Coordination Mechanism in the Construction of Beautiful Countryside in Jiangsu”(Project No.:Njpj2022-2-01)。
文摘In recent years,managing rural living environments has become a vital component of the rural revitalization strategy.Jiangsu Province,rich in economic and cultural resources,has accumulated valuable experience in exploring rural environmental governance by integrating culture and tourism.This research analyzes the practical logic of rural environmental governance in Jiangsu from both theoretical and practical perspectives.It emphasizes the importance of integrating culture and tourism to enhance environmental governance while addressing the associated challenges.The results show that the integration of culture and tourism not only enhances rural ecological environments and living facilities but also boosts regional economic development and the preservation of cultural resources.Nevertheless,there are still challenges in aspects such as the collaboration of stakeholders,the establishment of long-term mechanisms,and the application of digital technologies.Based on real cases in Jiangsu,this study suggests optimization strategies and policy recommendations to improve rural environmental governance within the framework of cultural and tourism integration.
基金supported in part by the Universityindustry Collaborative Education Program of the Ministry of Education under Grant No.202102383004。
文摘The advancement of Internet of Things(IoT)technology is driving industries toward intelligent digital transformation,highlighting the crucial role of software engineering.Despite this,the integration of software engineering into IoT engineering education remains underexplored.To address this gap,the School of Software at North University of China,in collaboration with QST Innovation Technology Group Co.,Ltd.(QST),has developed an innovative educational mechanism.This initiative focuses on the software engineering IoT track and optimizes the teaching process through the outcome-based education(OBE)concept.It incorporates military-industrial characteristics,introduces advanced information and technology curricula,and enhances laboratory infrastructure.The goal is to cultivate innovative talents with unique capabilities,thereby fostering the comprehensive development and application of IoT technology.
基金“Curriculum Ideological and Political Education”Demonstration Project of Chongqing University of Posts and Telecommunications:Design Thinking and Expression(Environmental Design)(XKCSZ2251)Construction and Practice of the Ability Training System for“Internet+”Design Talents to Serve Rural Revitalization(233231)。
文摘This study explores the integration path of ideological and political education in the course Design Thinking and Expression of environmental art design,aiming to enhance students’innovative thinking,social responsibility,and awareness of sustainable development.Based on the core philosophy of design thinking(people-oriented,problem-solving,and interdisciplinary collaboration)and the elements of ideological and political education in courses(moral education,cultural confidence,sustainable development,and social equity),the study proposes implementation paths for optimizing course objectives,adjusting course content,innovating teaching methods,and optimizing the evaluation system.Through project-based learning,situational teaching,and interdisciplinary collaboration,combined with practical cases such as historical district renewal,environmental design for rural revitalization,and green commercial space design,it has been verified that the effective integration of ideological and political elements in courses can enhance students’cultural identity,sense of social responsibility,and design innovation ability.This study provides theoretical support and practical demonstration for the ideological and political reform of environmental art design courses.In the future,interdisciplinary collaboration can be further deepened,social practice applications can be expanded,the evaluation system can be improved,and the systematic development of ideological and political courses can be promoted.
基金Project supported in part by the National Key Research and Development Program of China(Grant No.2021YFB2206504)the National Natural Science Foundation of China(Grant No.62235017)the China Postdoctoral Science Foundation(Grant No.2021M703125).
文摘The performance of optical interconnection has improved dramatically in recent years.Silicon-based optoelectronic heterogeneous integration is the key enabler to achieve high performance optical interconnection,which not only provides the optical gain which is absent from native Si substrates and enables complete photonic functionalities on chip,but also improves the system performance through advanced heterogeneous integrated packaging.This paper reviews recent progress of silicon-based optoelectronic heterogeneous integration in high performance optical interconnection.The research status,development trend and application of ultra-low loss optical waveguides,high-speed detectors,high-speed modulators,lasers and 2D,2.5D,3D and monolithic integration are focused on.
基金supported by National Natural Science Foundation of China(Grant No.52022078)Shaanxi Provincial Key Research and Development Program(Grant No.2021ZDLGY10-02,2019ZDLGY01-09)。
文摘As the manufacturing process of silicon-based integrated circuits(ICs)approaches its physical limit,the quantum effect of silicon-based field-effect transistors(FETs)has become increasingly evident.And the burgeoning carbon-based semiconductor technology has become one of the most disruptive technologies in the post-Moore era.As one-dimensional nanomaterials,carbon nanotubes(CNTs)are far superior to silicon at the same technology nodes of FETs because of their excellent electrical transport and scaling properties,rendering them the most competitive material in the next-generation ICs technology.However,certain challenges impede the industrialization of CNTs,particularly in terms of material preparation,which significantly hinders the development of CNT-based ICs.Focusing on CNT-based ICs technology,this review summarizes its main technical status,development trends,existing challenges,and future development directions.
基金Supported by National Natural Science Foundation of China(Grant No.52075036)Key Technologies Research and Development Program of China(Grant No.2022YFC3302204).
文摘The Chinese express delivery industry processes nearly 110 billion items in 2022,averaging an annual growth rate of 200%.Among the various types of sorting systems used for handling express items,cross-belt sorting systems stand out as the most crucial.However,despite their high degree of automation,the workload for operators has intensified owing to the surging volume of express items.In the era of Industry 5.0,it is imperative to adopt new technologies that not only enhance worker welfare but also improve the efficiency of cross-belt systems.Striking a balance between efficiency in handling express items and operator well-being is challenging.Digital twin technology offers a promising solution in this respect.A realization method of a human-machine integrated digital twin is proposed in this study,enabling the interaction of biological human bodies,virtual human bodies,virtual equipment,and logistics equipment in a closed loop,thus setting an operating framework.Key technologies in the proposed framework include a collection of heterogeneous data from multiple sources,construction of the relationship between operator fatigue and operation efficiency based on physiological measurements,virtual model construction,and an online optimization module based on real-time simulation.The feasibility of the proposed method was verified in an express distribution center.
基金supported by the National Science Foundation for Distinguished Young Scholars,China(82025021).
文摘Critical care medicine focuses on understanding the pathophysiological mechanisms and treatment approaches for life-threatening conditions,including sepsis,severe trauma/burns,hemorrhagic shock,heatstroke,and acute pancreatitis,all of which have high incidence rates.These conditions are primarily characterized by acute multi-organ dysfunction,with sudden onset,severe illness,and high mortality rates.Additionally,critical care treatment demands substantial medical resources,imposing significant economic burdens on patients’families and society.In recent years,critical care medicine has achieved notable progress,especially in multidisciplinary integration with immunology-based fields.Collaboration across disciplines has not only accelerated advancements in critical care but also propelled the rapid development of modern immunology.This paper provides an overview and assessment of the cross-disciplinary fusion between critical care medicine and immunology,exploring how these fields related extensions mutually enhance each other.It further analyzes China’s potential to become a global leader in this area within the next 5 to 10 years.
基金supported by the National Natural Science Foundation of China(NFSCGrant No.42030410)+2 种基金Laoshan Laboratory(No.LSKJ202202402)the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB40000000)the Startup Foundation for Introducing Talent of NUIST.
文摘El Niño-Southern Oscillation(ENSO)is the strongest interannual climate mode influencing the coupled ocean-atmosphere system in the tropical Pacific,and numerous dynamical and statistical models have been developed to simulate and predict it.In some simplified coupled ocean-atmosphere models,the relationship between sea surface temperature(SST)anomalies and wind stress(τ)anomalies can be constructed by statistical methods,such as singular value decomposition(SVD).In recent years,the applications of artificial intelligence(AI)to climate modeling have shown promising prospects,and the integrations of AI-based models with dynamical models are active areas of research.This study constructs U-Net models for representing the relationship between SSTAs andτanomalies in the tropical Pacific;the UNet-derivedτmodel,denoted asτUNet,is then used to replace the original SVD-basedτmodel of an intermediate coupled model(ICM),forming a newly AI-integrated ICM,referred to as ICM-UNet.The simulation results obtained from ICM-UNet demonstrate their ability to represent the spatiotemporal variability of oceanic and atmospheric anomaly fields in the equatorial Pacific.In the ocean-only case study,theτUNet-derived wind stress anomaly fields are used to force the ocean component of the ICM,the results of which also indicate reasonable simulations of typical ENSO events.These results demonstrate the feasibility of integrating an AI-derived model with a physics-based dynamical model for ENSO modeling studies.Furthermore,the successful integration of the dynamical ocean models with the AI-based atmospheric wind model provides a novel approach to ocean-atmosphere interaction modeling studies.
基金supported by the Swiss National Science Foundation(Grant No.189882)the National Natural Science Foundation of China(Grant No.41961134032)support provided by the New Investigator Award grant from the UK Engineering and Physical Sciences Research Council(Grant No.EP/V012169/1).
文摘In this study,we present a novel nodal integration-based particle finite element method(N-PFEM)designed for the dynamic analysis of saturated soils.Our approach incorporates the nodal integration technique into a generalised Hellinger-Reissner(HR)variational principle,creating an implicit PFEM formulation.To mitigate the volumetric locking issue in low-order elements,we employ a node-based strain smoothing technique.By discretising field variables at the centre of smoothing cells,we achieve nodal integration over cells,eliminating the need for sophisticated mapping operations after re-meshing in the PFEM.We express the discretised governing equations as a min-max optimisation problem,which is further reformulated as a standard second-order cone programming(SOCP)problem.Stresses,pore water pressure,and displacements are simultaneously determined using the advanced primal-dual interior point method.Consequently,our numerical model offers improved accuracy for stresses and pore water pressure compared to the displacement-based PFEM formulation.Numerical experiments demonstrate that the N-PFEM efficiently captures both transient and long-term hydro-mechanical behaviour of saturated soils with high accuracy,obviating the need for stabilisation or regularisation techniques commonly employed in other nodal integration-based PFEM approaches.This work holds significant implications for the development of robust and accurate numerical tools for studying saturated soil dynamics.
基金The help and support of owners of the dairy farms enrolled in this study is gratefully acknowledged.The financial support from the program of China Scholarship Council during the PhD study of Mengqi Wang in Canada is acknowledged(No.202008880009).
文摘Background Mastitis caused by multiple factors remains one of the most common and costly disease of the dairy industry.Multi-omics approaches enable the comprehensive investigation of the complex interactions between mul-tiple layers of information to provide a more holistic view of disease pathogenesis.Therefore,this study investigated the genomic and epigenomic signatures and the possible regulatory mechanisms underlying subclinical mastitis by integrating RNA sequencing data(mRNA and lncRNA),small RNA sequencing data(miRNA)and DNA methylation sequencing data of milk somatic cells from 10 healthy cows and 20 cows with naturally occurring subclinical mastitis caused by Staphylococcus aureus or Staphylococcus chromogenes.Results Functional investigation of the data sets through gene set analysis uncovered 3458 biological process GO terms and 170 KEGG pathways with altered activities during subclinical mastitis,provided further insights into subclin-ical mastitis and revealed the involvement of multi-omics signatures in the altered immune responses and impaired mammary gland productivity during subclinical mastitis.The abundant genomic and epigenomic signatures with sig-nificant alterations related to subclinical mastitis were observed,including 30,846,2552,1276 and 57 differential methylation haplotype blocks(dMHBs),differentially expressed genes(DEGs),lncRNAs(DELs)and miRNAs(DEMs),respectively.Next,5 factors presenting the principal variation of differential multi-omics signatures were identified.The important roles of Factor 1(DEG,DEM and DEL)and Factor 2(dMHB and DEM),in the regulation of immune defense and impaired mammary gland functions during subclinical mastitis were revealed.Each of the omics within Factors 1 and 2 explained about 20%of the source of variation in subclinical mastitis.Also,networks of impor-tant functional gene sets with the involvement of multi-omics signatures were demonstrated,which contributed to a comprehensive view of the possible regulatory mechanisms underlying subclinical mastitis.Furthermore,multi-omics integration enabled the association of the epigenomic regulatory factors(dMHBs,DELs and DEMs)of altered genes in important pathways,such as‘Staphylococcus aureus infection pathway’and‘natural killer cell mediated cyto-toxicity pathway’,etc.,which provides further insights into mastitis regulatory mechanisms.Moreover,few multi-omics signatures(14 dMHBs,25 DEGs,18 DELs and 5 DEMs)were identified as candidate discriminant signatures with capac-ity of distinguishing subclinical mastitis cows from healthy cows.Conclusion The integration of genomic and epigenomic data by multi-omics approaches in this study provided a better understanding of the molecular mechanisms underlying subclinical mastitis and identified multi-omics candidate discriminant signatures for subclinical mastitis,which may ultimately lead to the development of more effective mastitis control and management strategies.
基金supported by the National Nature Science Foun-dation of China(grant numbers:82141106,81630060)the National Key Research and Development Program of China(grant number:2021YFC2701204)+2 种基金Key Technology R&D Program of Hubei(grant num-ber:2024BCB057)Panyu District Science and Technology Plan Project(grant number:2020-Z04-014)Guangzhou Health Science and Tech-nology Project(grant number:20221A011118).
文摘Objective:We investigated the relation between man papillomavirus(HPV)integration status and the immediate risk of cervical intraepithelial neoplasia(CIN),as well as the triage strategy based on HPV integration test.Methods:4086 women aged 20 to 65 years in China were enrolled in 2015 for a prospective,population-based,clinical observational study to evaluate the triage performance of HPV integration.Cervical exfoliated cells were collected for HPV testing and cytologic test.If high-risk HPV was positive,HPV integration test was performed at baseline,2-year and 5-year follow-up.Results:At baseline,HPV integration was positively correlated with the severity of cervical pathology,ranging from 5.0%(15/301)in normal diagnosis,6.9%(4/58)in CIN1,31.0%(9/29)in CIN2,70%(14/20)in CIN3,and 100%(2/2)in cervical cancer(P<0.001).Compared with cytology,HPV integration exhibits comparable sensitivity and negative predictive value for the diagnosis of CIN3+,higher specificity(92.8%[90.2%-95.4%]vs.75.5%[71.2%-79.8%],P<0.001)and higher positive predictive value(36.4%[22.1%-50.6%]vs.15.2%[8.5%-21.8%],P<0.001).HPV integration testing strategy yielded a significantly lower colposcopy referral rate than cytology strategy(10.7%[44/410]vs.27.3%[112/410],P<0.001).The HPV integration-negative group exhibited the lowest immediate risk for CIN3+(1.6%)and accounted for the largest proportion of the total population(89.3%),when compared with the normal cytology group(risk,1.7%;proportion,72.7%).Conclusion:As a key molecular basis for the development of cervical cancer,HPV integration might be a promising triage strategy for HPV-positive patients.
