Granulocyte colony-stimulating factor (G-CSF ), granulocyte-microphage colony-stimulating factor (GM- CSF ) is specific hematopoietic regulating growth factor of granulocyte lineage, granulocyte-monocyte lineage, resp...Granulocyte colony-stimulating factor (G-CSF ), granulocyte-microphage colony-stimulating factor (GM- CSF ) is specific hematopoietic regulating growth factor of granulocyte lineage, granulocyte-monocyte lineage, respectively. G-CSF. GM-CSF can promote the proliferation, differentiation and mature of its hematopoietic progenitor and enhance the function of mature blood cell. Their gene recombinant human products have been widely applied to clinical practice. The effects of G-GSF. GM-CSF in clinical application are as follows (l ) reducing malignant tumor chemotherapy-related neutropenia, duration of neutropenia, infections and resulting treatment delays. (2 ) mobilizing peripheral blood stem progenitor cell and speeding hematopoietic reconstituation following allogeneic and autologous stem progenitor transplantation. The recent clinical application of G-CSF. GM-CSF has been summarized in this review.展开更多
文摘Granulocyte colony-stimulating factor (G-CSF ), granulocyte-microphage colony-stimulating factor (GM- CSF ) is specific hematopoietic regulating growth factor of granulocyte lineage, granulocyte-monocyte lineage, respectively. G-CSF. GM-CSF can promote the proliferation, differentiation and mature of its hematopoietic progenitor and enhance the function of mature blood cell. Their gene recombinant human products have been widely applied to clinical practice. The effects of G-GSF. GM-CSF in clinical application are as follows (l ) reducing malignant tumor chemotherapy-related neutropenia, duration of neutropenia, infections and resulting treatment delays. (2 ) mobilizing peripheral blood stem progenitor cell and speeding hematopoietic reconstituation following allogeneic and autologous stem progenitor transplantation. The recent clinical application of G-CSF. GM-CSF has been summarized in this review.
