目的:研究HSIL患者进行不同手术方式的处理,随后对患者进行随访,对患者后期HPV的转归结果进行分析。方法:搜集2023年1月至2024年1月就诊于我院的HSIL并接受手术治疗的患者90名,其中按手术方式的不同分为3组,分别是CKC组、LEEP组、锐扶...目的:研究HSIL患者进行不同手术方式的处理,随后对患者进行随访,对患者后期HPV的转归结果进行分析。方法:搜集2023年1月至2024年1月就诊于我院的HSIL并接受手术治疗的患者90名,其中按手术方式的不同分为3组,分别是CKC组、LEEP组、锐扶刀组各30名。对于不同手术方式的患者3、6、12个月进行HPV的检测。结果:① 三组患者一般资料对比,年龄、孕次、产次、是否绝经、有无阴道炎、HPV的感染情况对比,差异无统计学意义(P > 0.05);② 三组患者手术资料的对比,术后切缘状态、是否累腺,三组间比较差异无统计学意义(P > 0.05),锥切深度的不同在三组间比较差异有统计学意义(P 0.05);④ 将HPV的转阴情况进行多因素分析,可得出是否有阴道炎、是否累及腺体、是否绝经与HPV转阴情况有相关性(P 0.05)。结论:HSIL患者不同手术方式均有一定的治疗效果,且术后HPV转阴率与绝经、阴道炎、累腺因素相关。Study of HSIL patients who underwent different surgical modalities and were subsequently followed up to analyze the outcome of late HPV regression in patients. Methods: Ninety patients with HSIL who attended our hospital from January 2023 to January 2024 and underwent surgical treatment were collected, of which 30 patients were divided into three groups according to the different surgical methods, namely, 30 patients each in the CKC group, the LEEP group, and the Sharp Knife group. HPV testing was performed at 3, 6, and 12 months for patients with different surgical procedures. In the end ① Comparison of the general information of the three groups of patients, age, pregnancy, delivery, whether menopause, the presence of vaginitis, HPV infection comparison, the difference is not statistically significant (P > 0.05);② Comparison of the three groups of patients’ surgical data, postoperative margin status, whether the gland is tired, the difference is not statistically significant among the three groups (P > 0.05), the difference between the three groups of the cone depth of the different comparison of the three groups statistically significant (P 0.05);④ A multifactorial analysis of the HPV conversion status can be concluded that there is a correlation between whether or not there is vaginitis, whether or not there is gland involvement, and whether or not there is menopause, and the HPV conversion status (P 0.05). Conclude: The different surgical modalities in HSIL patients were effective, and the postoperative HPV conversion rate was correlated with menopause, vaginitis, and tired gland factors.展开更多
目的:研究维生素D对于女性泌尿生殖道沙眼衣原体感染的应用疗效分析。方法:搜集2023年1月至2024年1月就诊于我院的检测出沙眼衣原体阳性的患者40名,同时选择健康的志愿者40名作为对照组。分别抽取两组患者的血清羟基维生素D(25-(OH)D)...目的:研究维生素D对于女性泌尿生殖道沙眼衣原体感染的应用疗效分析。方法:搜集2023年1月至2024年1月就诊于我院的检测出沙眼衣原体阳性的患者40名,同时选择健康的志愿者40名作为对照组。分别抽取两组患者的血清羟基维生素D(25-(OH)D)的浓度进行对比,其中感染组的患者抽取血清前未进行相关治疗;对感染组患者进行治疗结束后的1个月的血清羟基维生素D(25-(OH)D)的浓度进行检测,对比治愈患者前后血清羟基维生素D(25-(OH)D)的浓度。结果:① CT感染组与健康组的血清25-(OH)D水平进行对比,两组间比较差异有统计学意义(P 0.05);② 将治愈患者与未治愈患者的血清25-(OH)D水平进行对比,治愈患者血清25-(OH)D水平为41.37 ± 21.03,未治愈患者血清25-(OH)D水平为29.47 ± 16.66,两组间比较差异有统计学意义(P 50 nmol/L者相比维生素D水平缺乏者的调整OR = 7.188,95%CI: 2.462, 21.147。结论:人泌尿生殖道沙眼衣原体感染及疗效降低与维生素D缺乏相关,血清维生素D水平降低可能会增加泌尿生殖道沙眼衣原体感染风险,并降低疗效。Purpose: Study of the efficacy of vitamin D in the application of Chlamydia trachomatis infection of the genitourinary tract in women. Method: Forty patients who tested positive for Chlamydia trachomatis and 40 healthy volunteers were collected from January 2023 to January 2024, and 40 healthy volunteers were selected as the control group. The serum hydroxyvitamin D (25-(OH)D) concentrations of the two groups of patients were extracted for comparison, in which the patients in the infected group did not undergo any relevant treatment before serum extraction;the serum hydroxyvitamin D(25-(OH)D) one month after the completion of treatment, and ere compared between before and after the cure of the patients. Result: ① The serum 25-(OH)D levels of the CT infected group were compared with those of the healthy group, statistically significant (P 50 nmol/L. Conclusion: Human genitourinary Chlamydia trachomatis infection and reduced efficacy are associated with vitamin D deficiency, and reduced serum vitamin D levels may increase the risk of genitourinary Chlamydia trachomatis infection and reduce efficacy.展开更多
文摘目的:研究HSIL患者进行不同手术方式的处理,随后对患者进行随访,对患者后期HPV的转归结果进行分析。方法:搜集2023年1月至2024年1月就诊于我院的HSIL并接受手术治疗的患者90名,其中按手术方式的不同分为3组,分别是CKC组、LEEP组、锐扶刀组各30名。对于不同手术方式的患者3、6、12个月进行HPV的检测。结果:① 三组患者一般资料对比,年龄、孕次、产次、是否绝经、有无阴道炎、HPV的感染情况对比,差异无统计学意义(P > 0.05);② 三组患者手术资料的对比,术后切缘状态、是否累腺,三组间比较差异无统计学意义(P > 0.05),锥切深度的不同在三组间比较差异有统计学意义(P 0.05);④ 将HPV的转阴情况进行多因素分析,可得出是否有阴道炎、是否累及腺体、是否绝经与HPV转阴情况有相关性(P 0.05)。结论:HSIL患者不同手术方式均有一定的治疗效果,且术后HPV转阴率与绝经、阴道炎、累腺因素相关。Study of HSIL patients who underwent different surgical modalities and were subsequently followed up to analyze the outcome of late HPV regression in patients. Methods: Ninety patients with HSIL who attended our hospital from January 2023 to January 2024 and underwent surgical treatment were collected, of which 30 patients were divided into three groups according to the different surgical methods, namely, 30 patients each in the CKC group, the LEEP group, and the Sharp Knife group. HPV testing was performed at 3, 6, and 12 months for patients with different surgical procedures. In the end ① Comparison of the general information of the three groups of patients, age, pregnancy, delivery, whether menopause, the presence of vaginitis, HPV infection comparison, the difference is not statistically significant (P > 0.05);② Comparison of the three groups of patients’ surgical data, postoperative margin status, whether the gland is tired, the difference is not statistically significant among the three groups (P > 0.05), the difference between the three groups of the cone depth of the different comparison of the three groups statistically significant (P 0.05);④ A multifactorial analysis of the HPV conversion status can be concluded that there is a correlation between whether or not there is vaginitis, whether or not there is gland involvement, and whether or not there is menopause, and the HPV conversion status (P 0.05). Conclude: The different surgical modalities in HSIL patients were effective, and the postoperative HPV conversion rate was correlated with menopause, vaginitis, and tired gland factors.
文摘目的:研究维生素D对于女性泌尿生殖道沙眼衣原体感染的应用疗效分析。方法:搜集2023年1月至2024年1月就诊于我院的检测出沙眼衣原体阳性的患者40名,同时选择健康的志愿者40名作为对照组。分别抽取两组患者的血清羟基维生素D(25-(OH)D)的浓度进行对比,其中感染组的患者抽取血清前未进行相关治疗;对感染组患者进行治疗结束后的1个月的血清羟基维生素D(25-(OH)D)的浓度进行检测,对比治愈患者前后血清羟基维生素D(25-(OH)D)的浓度。结果:① CT感染组与健康组的血清25-(OH)D水平进行对比,两组间比较差异有统计学意义(P 0.05);② 将治愈患者与未治愈患者的血清25-(OH)D水平进行对比,治愈患者血清25-(OH)D水平为41.37 ± 21.03,未治愈患者血清25-(OH)D水平为29.47 ± 16.66,两组间比较差异有统计学意义(P 50 nmol/L者相比维生素D水平缺乏者的调整OR = 7.188,95%CI: 2.462, 21.147。结论:人泌尿生殖道沙眼衣原体感染及疗效降低与维生素D缺乏相关,血清维生素D水平降低可能会增加泌尿生殖道沙眼衣原体感染风险,并降低疗效。Purpose: Study of the efficacy of vitamin D in the application of Chlamydia trachomatis infection of the genitourinary tract in women. Method: Forty patients who tested positive for Chlamydia trachomatis and 40 healthy volunteers were collected from January 2023 to January 2024, and 40 healthy volunteers were selected as the control group. The serum hydroxyvitamin D (25-(OH)D) concentrations of the two groups of patients were extracted for comparison, in which the patients in the infected group did not undergo any relevant treatment before serum extraction;the serum hydroxyvitamin D(25-(OH)D) one month after the completion of treatment, and ere compared between before and after the cure of the patients. Result: ① The serum 25-(OH)D levels of the CT infected group were compared with those of the healthy group, statistically significant (P 50 nmol/L. Conclusion: Human genitourinary Chlamydia trachomatis infection and reduced efficacy are associated with vitamin D deficiency, and reduced serum vitamin D levels may increase the risk of genitourinary Chlamydia trachomatis infection and reduce efficacy.
