Objective To observe the value of isotropic volumetric MRI for displaying perineural spread(PNS)of cranial nerve(CN)in nasopharyngeal carcinoma.Methods Eighty-seven patients with pathologically proven nasopharyngeal c...Objective To observe the value of isotropic volumetric MRI for displaying perineural spread(PNS)of cranial nerve(CN)in nasopharyngeal carcinoma.Methods Eighty-seven patients with pathologically proven nasopharyngeal carcinoma were prospectively enrolled.MR scanning,including three-dimensional liver acquisition with volume acceleration-flexible(3D LAVA_Flex)image,T2WI with fat suppression(T2WI-FS),T1WI,contrast enhancement(CE)T1WI-FS of nasopharynx and neck region were performed.The displaying rates of CN PNS were evaluated and compared between 3D LAVA_Flex and T2WI-FS,T1WI,CE-T1WI-FS at patient level,CN group level and neural level,respectively.Results The displaying rate of CN PNS in all 87 nasopharyngeal carcinoma patients by 3D LAVA_Flex sequence was 49.43%(43/87),higher than that of conventional MRI(30/87,34.48%,P=0.001).Among 59 patients with advanced nasopharyngeal carcinoma diagnosed with conventional sequences,the displaying rate of CN PNS was 71.19%(42/59)by 3D LAVA-Flex sequence,higher than that of conventional MRI(30/59,50.85%,P=0.001).At both patient level and posterior CN level,significant differences of the displaying rate of CN PNS were found between 3D LAVA-Flex sequence and T2WI-FS,T1WI,CE-T1WI-FS,while at CN level,the displaying rates of mandibular nerve PNS,CNⅨ—ⅪPNS in jugular foramen(P<0.05)and CNⅨ—ⅫPNS in carotid space of 3D LAVA_Flex sequence were all significantly higher than that of T2WI-FS,T1WI and CE-T1WI-FS(all P<0.05),of PNS of CNⅢ—Ⅴin cavernous sinus were higher than that of T2WI-FS(P<0.05),while of PNS of hypoglossal nerve were significantly higher than that of T2WI-FS and T1WI(both P<0.05).Conclusion 3D LAVA_Flex sequence could be used to effectively display CN PNS of nasopharyngeal carcinoma.展开更多
目的探讨不同机架角度和多叶准直器(MLC)角度对容积旋转调强放射治疗(VMAT)及静态调强放射治疗(IMRT)MLC叶片机械到位精度的影响。方法在Eclipse 15.5治疗计划系统上导入并编辑对应的MLC叶片机械到位精度测试计划,并在瓦里安TrueBeam直...目的探讨不同机架角度和多叶准直器(MLC)角度对容积旋转调强放射治疗(VMAT)及静态调强放射治疗(IMRT)MLC叶片机械到位精度的影响。方法在Eclipse 15.5治疗计划系统上导入并编辑对应的MLC叶片机械到位精度测试计划,并在瓦里安TrueBeam直线加速器上进行以下投照测试:直接采用与直线加速器匹配的Picket Fence测试计划进行VMAT的MLC叶片机械到位精度测试,测试机架角度包括0°、90°、180°和270°;设置机架角度分别为0°、90°、180°和270°,MLC角度为0°,进行IMRT的MLC叶片机械到位精度测试;设置机架角度分别为90°和270°,MLC角度分别为10°、20°和30°,进行IMRT的MLC叶片机械到位精度测试。采用电子射野影像装置(EPID,针对VMAT和IMRT所有测试)和胶片(仅针对IMRT测试)对测试计划进行投照成像,采用DoseLab Version 7.0软件(针对VMAT和IMRT所有测试数据)和RIT complete Version 6.10软件(仅针对IMRT测试数据)导入并分析EPID影像的MLC叶片机械到位精度,采用Film QA Pro Version 4.0软件分析胶片的MLC叶片机械到位精度。结果DoseLab Version 7.0软件针对EPID影像的分析结果显示,4种机架角度下VMAT的MLC叶片机械到位精度平均偏差均<0.20 mm,设置到位精度容差为0.50 mm,栅栏野通过率为100%;4种机架角度下IMRT的MLC叶片机械到位精度平均偏差均≤0.50 mm,且均大于VMAT的MLC叶片机械到位精度平均偏差,设置到位精度容差为0.50 mm,栅栏野通过率>95%。RIT complete Version 6.10软件针对EPID影像的分析结果及Film QA Pro Version 4.0软件针对胶片的分析结果均显示,机架角度为90°和270°时,不同MLC角度的MLC叶片机械到位精度平均偏差均<1 mm,符合美国医学物理学家协会(AAPM)TG-142报告要求;且机架角度90°和270°的MLC叶片机械到位精度偏差呈相反趋势。结论不同机架角度和MLC角度下,VMAT和IMRT的MLC叶片机械到位精度均符合标准。但MLC叶片机械到位精度测试对于放射治疗计划剂量的精准投照至关重要,因此需要严格按照相关标准定期进行质量控制测试,检查叶片到位的精度及重复性。展开更多
目的 分析“以人为本”护理理念的护理干预对直肠癌合并高血压放化疗患者焦虑自评量表(Self-Rating Anxiety Scale,SAS)评分及健康状况调查简表(the MOS item short from health survey,SF-36)的价值。方法 选取本科室正接受放化疗的直...目的 分析“以人为本”护理理念的护理干预对直肠癌合并高血压放化疗患者焦虑自评量表(Self-Rating Anxiety Scale,SAS)评分及健康状况调查简表(the MOS item short from health survey,SF-36)的价值。方法 选取本科室正接受放化疗的直肠癌合并高血压患者58例,利用随机数字表法进行分组,分为对照组与实验组,每组29例,实验组采用“以人为本”护理理念的护理干预,对照组采用常规护理。比较两组干预前后血压水平、SAS和SF-36得分情况。结果 实验组收缩压、舒张压及SAS评分均低于对照组,SF-36评分高于对照组(P<0.05),结论 “以人为本”护理理念的护理干预可有效地控制患者血压,降低患者焦虑程度,提高生活质量。展开更多
文摘Objective To observe the value of isotropic volumetric MRI for displaying perineural spread(PNS)of cranial nerve(CN)in nasopharyngeal carcinoma.Methods Eighty-seven patients with pathologically proven nasopharyngeal carcinoma were prospectively enrolled.MR scanning,including three-dimensional liver acquisition with volume acceleration-flexible(3D LAVA_Flex)image,T2WI with fat suppression(T2WI-FS),T1WI,contrast enhancement(CE)T1WI-FS of nasopharynx and neck region were performed.The displaying rates of CN PNS were evaluated and compared between 3D LAVA_Flex and T2WI-FS,T1WI,CE-T1WI-FS at patient level,CN group level and neural level,respectively.Results The displaying rate of CN PNS in all 87 nasopharyngeal carcinoma patients by 3D LAVA_Flex sequence was 49.43%(43/87),higher than that of conventional MRI(30/87,34.48%,P=0.001).Among 59 patients with advanced nasopharyngeal carcinoma diagnosed with conventional sequences,the displaying rate of CN PNS was 71.19%(42/59)by 3D LAVA-Flex sequence,higher than that of conventional MRI(30/59,50.85%,P=0.001).At both patient level and posterior CN level,significant differences of the displaying rate of CN PNS were found between 3D LAVA-Flex sequence and T2WI-FS,T1WI,CE-T1WI-FS,while at CN level,the displaying rates of mandibular nerve PNS,CNⅨ—ⅪPNS in jugular foramen(P<0.05)and CNⅨ—ⅫPNS in carotid space of 3D LAVA_Flex sequence were all significantly higher than that of T2WI-FS,T1WI and CE-T1WI-FS(all P<0.05),of PNS of CNⅢ—Ⅴin cavernous sinus were higher than that of T2WI-FS(P<0.05),while of PNS of hypoglossal nerve were significantly higher than that of T2WI-FS and T1WI(both P<0.05).Conclusion 3D LAVA_Flex sequence could be used to effectively display CN PNS of nasopharyngeal carcinoma.
文摘目的探讨不同机架角度和多叶准直器(MLC)角度对容积旋转调强放射治疗(VMAT)及静态调强放射治疗(IMRT)MLC叶片机械到位精度的影响。方法在Eclipse 15.5治疗计划系统上导入并编辑对应的MLC叶片机械到位精度测试计划,并在瓦里安TrueBeam直线加速器上进行以下投照测试:直接采用与直线加速器匹配的Picket Fence测试计划进行VMAT的MLC叶片机械到位精度测试,测试机架角度包括0°、90°、180°和270°;设置机架角度分别为0°、90°、180°和270°,MLC角度为0°,进行IMRT的MLC叶片机械到位精度测试;设置机架角度分别为90°和270°,MLC角度分别为10°、20°和30°,进行IMRT的MLC叶片机械到位精度测试。采用电子射野影像装置(EPID,针对VMAT和IMRT所有测试)和胶片(仅针对IMRT测试)对测试计划进行投照成像,采用DoseLab Version 7.0软件(针对VMAT和IMRT所有测试数据)和RIT complete Version 6.10软件(仅针对IMRT测试数据)导入并分析EPID影像的MLC叶片机械到位精度,采用Film QA Pro Version 4.0软件分析胶片的MLC叶片机械到位精度。结果DoseLab Version 7.0软件针对EPID影像的分析结果显示,4种机架角度下VMAT的MLC叶片机械到位精度平均偏差均<0.20 mm,设置到位精度容差为0.50 mm,栅栏野通过率为100%;4种机架角度下IMRT的MLC叶片机械到位精度平均偏差均≤0.50 mm,且均大于VMAT的MLC叶片机械到位精度平均偏差,设置到位精度容差为0.50 mm,栅栏野通过率>95%。RIT complete Version 6.10软件针对EPID影像的分析结果及Film QA Pro Version 4.0软件针对胶片的分析结果均显示,机架角度为90°和270°时,不同MLC角度的MLC叶片机械到位精度平均偏差均<1 mm,符合美国医学物理学家协会(AAPM)TG-142报告要求;且机架角度90°和270°的MLC叶片机械到位精度偏差呈相反趋势。结论不同机架角度和MLC角度下,VMAT和IMRT的MLC叶片机械到位精度均符合标准。但MLC叶片机械到位精度测试对于放射治疗计划剂量的精准投照至关重要,因此需要严格按照相关标准定期进行质量控制测试,检查叶片到位的精度及重复性。
文摘目的 分析“以人为本”护理理念的护理干预对直肠癌合并高血压放化疗患者焦虑自评量表(Self-Rating Anxiety Scale,SAS)评分及健康状况调查简表(the MOS item short from health survey,SF-36)的价值。方法 选取本科室正接受放化疗的直肠癌合并高血压患者58例,利用随机数字表法进行分组,分为对照组与实验组,每组29例,实验组采用“以人为本”护理理念的护理干预,对照组采用常规护理。比较两组干预前后血压水平、SAS和SF-36得分情况。结果 实验组收缩压、舒张压及SAS评分均低于对照组,SF-36评分高于对照组(P<0.05),结论 “以人为本”护理理念的护理干预可有效地控制患者血压,降低患者焦虑程度,提高生活质量。
