目的:系统评价人工鼻(HME)使用对人工气道患者肺部感染的预防效果。方法:计算机检索Cochrane图书馆、JBI循证护理中心图书馆、MEDLINE、Embase、Pubmed、中国知网数据库(CNKI)、维普数据库(VIP)、万方数据库,收集所有关于人工鼻预防人...目的:系统评价人工鼻(HME)使用对人工气道患者肺部感染的预防效果。方法:计算机检索Cochrane图书馆、JBI循证护理中心图书馆、MEDLINE、Embase、Pubmed、中国知网数据库(CNKI)、维普数据库(VIP)、万方数据库,收集所有关于人工鼻预防人工气道患者肺部感染的随机对照试验和临床对照试验。2名研究者按照纳入和排除标准独立检索文献、筛选文献、评价纳入文献的质量,并提取资料,使用Rev Man 5.3软件进行Meta分析。结果:共纳入14篇文献,均为RCT。Meta分析结果显示:与未使用人工鼻相比,人工鼻可以预防人工气道患者肺部感染发生[随机效应模型OR=0.76,95%CI(0.47,1.20)],差异具有统计学意义;对患者病死率的影响差异无统计学意义[随机效应模型OR=0.97,95%CI(0.65,1.46)]。结论:人工鼻可以降低人工气道患者肺部感染的发生率,建议临床推广使用。展开更多
A Review Many studies indicate that apoptosis is involved in the progression of congestive heart failure. At present, mechanisms that mitochondria regulates cell apoptosis is widely accepted.Cardiac myocytes have abun...A Review Many studies indicate that apoptosis is involved in the progression of congestive heart failure. At present, mechanisms that mitochondria regulates cell apoptosis is widely accepted.Cardiac myocytes have abundant mitochondria,which plays an important role in maintenance of cell physiological function. Recent studies find that cardiac energy metabolic shifts occur as a normal response to diverse physiologic and dietary conditions and as a component of the pathophysiologic processes which accompany cardiac hypertrophy, heart failure, and myocardial ischemia.Both clinical and experimental studies show that cardiac function can be improved and apoptosis is inhibited by intervention in energetic metabolism of myocytes. [展开更多
文摘目的:系统评价人工鼻(HME)使用对人工气道患者肺部感染的预防效果。方法:计算机检索Cochrane图书馆、JBI循证护理中心图书馆、MEDLINE、Embase、Pubmed、中国知网数据库(CNKI)、维普数据库(VIP)、万方数据库,收集所有关于人工鼻预防人工气道患者肺部感染的随机对照试验和临床对照试验。2名研究者按照纳入和排除标准独立检索文献、筛选文献、评价纳入文献的质量,并提取资料,使用Rev Man 5.3软件进行Meta分析。结果:共纳入14篇文献,均为RCT。Meta分析结果显示:与未使用人工鼻相比,人工鼻可以预防人工气道患者肺部感染发生[随机效应模型OR=0.76,95%CI(0.47,1.20)],差异具有统计学意义;对患者病死率的影响差异无统计学意义[随机效应模型OR=0.97,95%CI(0.65,1.46)]。结论:人工鼻可以降低人工气道患者肺部感染的发生率,建议临床推广使用。
文摘A Review Many studies indicate that apoptosis is involved in the progression of congestive heart failure. At present, mechanisms that mitochondria regulates cell apoptosis is widely accepted.Cardiac myocytes have abundant mitochondria,which plays an important role in maintenance of cell physiological function. Recent studies find that cardiac energy metabolic shifts occur as a normal response to diverse physiologic and dietary conditions and as a component of the pathophysiologic processes which accompany cardiac hypertrophy, heart failure, and myocardial ischemia.Both clinical and experimental studies show that cardiac function can be improved and apoptosis is inhibited by intervention in energetic metabolism of myocytes. [
